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Sunday, December 14, 2008

The Benefits of Green Tea - Cancer


Compounds inside Green Tea that are consideration to do someone a good turn opposition cancer:

Catechins

A green tea leaf contains catechins, they are the components that disintegrate a bitter tolerate to the tea.

EGCG (epigallocatechin gallate) accounts for the reason that 10%-50% of the number green tea catechins. By virtue of its screwy stereochemical structure, EGCG possesses a great deal of more potent anti-oxidant attributes than the peculiar catechins created inside green tea furthermore plays an worthy role inside preventing cancer furthermore cardiovascular diseases. ECGC eliminate oxidised between engagements radicals from the body which prevents harm to the cells furthermore DNA. The anti oxidant assets of EGCG are adjudged 100 more long method aways more efficient than vitamin C furthermore 25 long method aways more efficient than vitamin E. (http://www.herbs-tech.com/product/egcg.asp)

Flavonoids

Flavonoids are put pigments; they are the brightly coloured chemical constituents created inside various spanking new fruits furthermore vegetables. Flavonoids are main for the reason that processing vitamin C furthermore are needed to maintain capillary walls. They may aid inside protecting opposition infection furthermore deficiency can effect inside a trend to bruise easily.

Health benefits

Reduces the jeopardy of cancer

Acting components: Flavonoids furthermore Catechins

How:

Carcinogens are cancer evoking agents. Phytochemicals may weigh down carcinogens from forming. Flavonoids are a form of phytochemical created inside Green tea. Experimental investigations submit to shown that tea furthermore tea polyphenols submit to anti-carcinogenic assets opposition breast cancer.¹

Studies yet suggest that ECGC may cut back the jeopardy of cancer.²

A population-based, case-control exploration of breast cancer amid Chinese, Japanese furthermore Filipino gentlemen inside Los Angeles County suggested an inverse link between Green tea intake furthermore the civilization of breast cancer. ³ Similar exploration was finished as well as gentlemen inside Italy which showed a equivalent inverse link.⁴

Results from animal investigations furthermore feasible cancer inhibitory streets may possibly engagement applicable to human cancer prevention. The solution furthermore feasible applications are chatted inside a exploration by C.S Yang et al. 2000. 

‘Free radicals defy healthy cells, which alters their DNA, granting tumors [sic] to grow. Antioxidants are substances that curtail the oxidation system furthermore conduct because protective agents. Antioxidants Research is underway to examine the role of antioxidants inside reducing the jeopardy of arising cancer. ’

(http://cancer.stanford.edu/information/nutritionAndCancer/reduceRisk/)

Catechins created inside green tea are distinguished for the reason that their antioxidant properties.⁶

(http://www.herbs-tech.com/product/egcg.asp)

Studies

¹Can-Lan Sun , Jian-Min Yuan, Woon-Puay Koh furthermore Mimi C. Yu Green tea, black tea furthermore breast cancer risk: a meta-analysis of epidemiological investigations Carcinogenesis 2006 27(7):1310-1315

² Maryam R. Sartippour, Zhi-Ming Shao, David Heber, Perrin Beatty, Liping Zhang, Canhui Liu, Lee Ellis, Wen Liu, Vay Liang Go furthermore Mai N. Brooks Green Tea Inhibits Vascular Endothelial Growth Factor (VEGF) Induction inside Human Breast Cancer Cells Journal of Nutrition. 2002 132:2307-2311

³Anna H. Wu , Mimi C. Yu , Chiu-Chen Tseng , Jean Hankin , Malcolm C. Pike. Green tea furthermore jeopardy of breast cancer inside Asian Americans. International Journal of Cancer. Sept. 10 106(4) :574-579.

Cristina Bosetti, Luana Spertini, Maria Parpinel, Patrizia Gnagnarella, Pagona Lagiou, Eva Negri, Silvia Franceschi, Maurizio Montella, Julie Peterson, Johanna Dwyer, Attilio Giacosa furthermore Carlo La Vecchia Flavonoids furthermore breast cancer jeopardy inside Italy. Cancer Epidemiology Biomarkers & Prevention April 2005 Vol. 14, 805-808,

Chung S. Yang, Jee Y. Chung, Guang-yu Yang, Saranjit K. Chhabra furthermore Mao-Jung Lee. Tea furthermore tea polyphenols inside cancer prevention. Journal of Nutrition. 2000;130:472S-478S..

⁶Balz Frei furthermore Jane V. Higdon Antioxidant Activity of Tea Polyphenols In Vivo: Evidence from Animal Studies Journal of Nutrition October 2003 133:3275S-3284S

Restrains tumours

Acting component: Catechins (EGCG furthermore ECG)

How:

EGCG stops the outburst of tumours by producing apoptosis¹ (process of cell self destruction), reducing cell-growth furthermore disrupting the cell-cycle. ²

EGCG suppresses the outburst of cancerous cells, ECG inside sundry cases was created to engagement more efficient because suppressing outburst than EGCG. ³ Green tea contains both of these Catechins.

Angiogenesis is the outburst of up to date blood vessels from pre-existing capillaries. This system is involved inside the civilization of cancer. Angiogenesis is necessary for the reason that tumour growth, because it presents minerals furthermore oxygen for the reason that the growing tumour. A likelihood mechanism by which green tea may weigh down cancer civilization is ready the impediment of angiogenesis.⁴

Researchers at the University of Murcia inside Spain (UMU) furthermore the John Innes Center (JIC) inside Norwich submit to shown that EGCG prevents cancer cells from growing by binding to a specific enzyme.

-Research is published inside the International Journal for the reason that Cancer Research.

Studies

¹ Rajesh L. Thangapazham, Anoop K. Singh, Anuj Sharma, James Warren, Jaya P. Gaddipati furthermore Radha K. Maheshwari. Green tea polyphenols furthermore its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells inside vitro furthermore inside vivo. Cancer Lett. Epub March 3, 2006. Vergote D.; Cren-OlivĂ© C.; Chopin V.; Toillon R-A.; Rolando C.; Hondermarck H.; Bourhis X.L. (-)-Epigallocatechin (GC) of green tea induces apoptosis of human breast cancer cells although not of their standard counterparts. Breast Cancer Res Treat. 2002 76, 3:195-201

²Vaqar M. Adhami, Nihal Ahmad furthermore Hasan Mukhtar Molecular Targets for the reason that Green Tea inside Prostate Cancer Prevention The Journal of Nutrition (July 2003) 133:2417S-2424S

N Ahmad, DK Feyes, AL Nieminen, R Agarwal furthermore H Mukhtar Green tea constituent epigallocatechin-3-gallate furthermore induction of apoptosis furthermore cell battery arrest inside human carcinoma cells Journal Of The National Cancer Institute 1997, Vol 89, 1881-1886

Bigelow RL, Cardelli JA. The green tea catechins, (-)-Epigallocatechin-3-gallate (EGCG) furthermore (-)-Epicatechin-3-gallate (ECG), curtail HGF/Met signaling inside immortalized furthermore tumorigenic breast epithelial cells. Oncogene. 2006 25, 13:1922-30

³Mepur H. Ravindranath, Thiruverkadu S. Saravanan, Clarence C. Monteclaro, Naftali Presser, Xing Ye, Senthamil R. Selvan furthermore Stanley Brosman Epicatechins Purified from Green Tea (Camellia sinensis) Differentially Suppress Growth of Gender-Dependent Human Cancer Cell Lines Evid Based Complement Alternat Med. 2006 Jun ;3:237-47

⁴Rodriguez SK, Guo W, Liu L, Band MA, Paulson EK, Meydani M. Green tea catechin, epigallocatechin-3-gallate, inhibits vascular endothelial outburst factor angiogenic signaling by disrupting the formation of a receptor complex. International Journal of Cancer 2006;118(7):1635-44. Jian-Min Yuan , Woon-Puay Koh , Can-Lan Sun , Hin-Peng Lee furthermore Mimi C. Yu . Green tea intake, ACE gene polymorphism furthermore breast cancer jeopardy amid Chinese gentlemen inside Singapore. Carcinogenesis. 2005 26, 8:1389-94,

Helps the sensation of cancer treatments

Acting Components: Catechin (EGCG)

How:

Radiation treatment for the reason that cancer can advertise angiogenesis (the outburst of up to date blood vessels from pre-existing capillaries providing minerals furthermore oxygen for the reason that the growing tumour) ECGC catechins submit to anti-angiogenic assets that may perhaps do someone a good turn to counteract this.¹

Studies

¹Annabi B, Lee YT, Martel C, Pilorget A, Bahary JP, Beliveau R Radiation induced-tubulogenesis inside endothelial cells is antagonized by the antiangiogenic assets of green tea polyphenol (-) epigallocatechin-3-gallate. Journal of Cancer, Biology furthermore Therapy 2003 Nov-Dec;2(6):642-9

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